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Airlia C. S. Thompson, Vivian Lien, Paula Campbell, Giovanni Bosco
Department of the Molecular and Cellular Biology

Do Cancer Genes Control Cell and Nuclear Size?

Abstract. There is a limited amount of information regarding what genes regulate cell and nuclear size. The mis-regulation of cell and nuclear size is a reoccurring theme in many human diseases, including cancer. To fully comprehend the cell cycle, and therefore cancer, it is imperative that the development of a cell be wholly understood. Defining the individual roles of specific cell cycle genes in the regulation of cell and nuclear size is the first step towards divulging how an entire tissue is ultimately developmentally regulated. Using the fruit fly, Drosophila melanogaster as a model, the affect of over-expression of specific cell cycle genes on cell and nuclear size is currently under investigation.

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Hanane Seaton, Dr. Mark Brabant, Dr. Giovanni Bosco
Department of the Molecular and Cellular Biology

A Synthetic Lethal Screen for Interactors of the RB Tumor Supressor

Abstract. The goal of this research is to find drug inhibitors to the tumors cause
by the mutation in the Rb gene (The Rb gene is responsible for regulating cell proliferation). The idea is to find a specific gene who's function can be compromised and by that cause death in the cells carrying the mutated Rb gene.

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Anne M Kakarala, Anya Sukhina, Charles M Higgins
Department of Electrical and Computer Engineering

Terrestrial Visual Navigation

Abstract. We elaborated biological small-field tracking algorithm and developed a neuromorphic vision chip emulating small target tracking in the fly. To achieve this we are developing a custom-built robot using two such chips to do visual navigation, specifically obstacle avoidance and target tracking.

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Beatrice Fankem, Dr. Kevin Mc Neill
Department of Electrical and Computer Engineering

Investigating the Application of Verilog VHDL:
modeling in sensor networking systems

Abstract. The ECE department has initiated a research's program into sensing systems. A key goal is to understand how to effectively build large-scale systems with thousands of sensors and apply these systems to important problems. In these systems, the sensor is a critical element that provides the interface between the real world and the virtual world. My work has focused on investigating the use of computer engineering modeling tools to help in the design of sensor platforms through the use of simulation.

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Olivia Ramirez, Dr. Fleischman
Civil Engineering Structural Division

Modular Steel Connections/ANSYS

Abstract. A steel connection is used in buildings to connect beams and columns. During a 1994 earthquake in Northridge it was found that anumber of connections fractured and experienced significant deformation. Dr. Fleishman and graduate students are developing new modular connections using a casting technology. ANSYS is used in creating a 3-dimensional simulation model. After the program runs the simulation is collected, charted and studied. I worked on the following; learned how to operate ANSYS, run simulations on different bolts, and changing parameters in a traditional steel connection in order to come up with a design that reduces the risk of premature failure in an earthquake.

For additional information: http://www.u.arizona.edu./~asumer

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Maria T. Williams
Department of Chemistry

Flavolipid Syntheses

Abstract. Two recently discovered and characterized substances produce by soil bacteria from Mount Lemmon, termed 6S, 6S - and (S,(S-flavolipids (2 and 3), were synthesized, confirming their structures and making them available for the testing of their detergent activities.

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Team Members: Cris Delfin, Roya Adeli, Hyeon Jeong Kim, Fred Todd, Stephanie Witt
Team Advisor: Dr. Rozenblit
Inventor : Rob Lucas

PROJECT C.A.R.E.
Cardiac Action Reaction Evaluation

A Project launched by the Electrical Computer and Engineering Department in conjunction with the Sarver Heart Clinic and School of Medicine to modify the recently developed CARE pad.

Abstract. Project CARE (Cardiac Action-Reaction Evaluator) was formed to assist in the creation of hardware interfaces for a remote stethoscope device that goes by the moniker of “CARE Pad System”. The purpose of this device will be not only to non-invasively monitor pulse and heart energy, but also to hopefully serve as an early diagnostic tool for all heart problems, but especially Congestive Heart Failure (CHF), which is particularly difficult to correctly diagnose using the current technology. The current problem with the technology is that there is an approximately 6 Hz resonant frequency caused by the chest cavity of the patient. This resonant frequency prevents easy discernment of the heart signal from the noise. The proposed hardware solution is a 6-hertz adjustable notch filter and a computer interface designed to go into an Analog to Digital converter. . The expected result is project is a machine that removes the approximately 6 Hz resonant frequency of the chest cavity, and also creates an input to a computer, where the signal can be viewed and recorded.